Research Officer (Ref:DMSMC)

Research Officer (Ref:DMSMC)

Singapore Health Services Pte Ltd
2-5 years
Not Specified

Job Description

Job Description
We are looking for a highly motivated and talented individual with passion in cancer genomics, biology and radiation research to join the Tan Chin Tuan Laboratory of Optical Imaging, Photodynamic and Proton Therapy - Precision Radiation Oncology Programme (PROP). The scope of the projects conducted under the premise of PROP includes 1) early- and late-phase clinical trials; 2) cancer genomics and data science; and 3) translational cancer and radiation biology. For this role, you will be mainly working with the Principal Investigator (PI) and the research teams under Theme 2. The projects involve studying cancer genomics of two main cancers, nasopharyngeal and prostate cancer, and the development of risk stratification models or identification of novel biomarkers for radioresistance. Samples from consented patients will be used for next generation sequencing and/or microarray to generate big data for further analysis by our data scientists. You will be involved in inter-departmental collaborations with oncologists, pathologists, scientists, and local and international collaborators. You will also be directly supervised and mentored by a Ph.D. Research Fellow (RF) and other senior staff with extensive experience.
You will participate in the following activities:
- Perform experiments based on existing SOP to process clinical research patient samples into useful patient data.
- Design and optimise new experimental protocol for new projects when necessary.
- Maintaining a complete and updated biobank and database of collected patient samples.
- Perform QA and QC to validate experimentally-derived patient data.
- Assist PI/co-investigators in preparing annual reports, conference presentations, manuscripts and reviews for publication, and grant/patent applications.
- Participate in research activities, lab meetings/presentations and audits under the mentorship of senior research staff.
- Maintain inventory and purchase reagents, consumables and equipment when required.
- Work with other researchers and doctors in research and clinical teams, as well as external science collaborators and other administrative teams.
Job Requirements
- B.Sc. degree in Biomedical/Life Sciences, or related fields.
- At least 2 years of research experience in molecular biology is necessary.
- Previous experience in skills such as cryosectioning, paraffin sectioning, IHC staining, H&E staining, blood sample processing, DNA/RNA extraction for next generation sequencing will be a plus.
- Prioritises proper handling, processing and documentation of patient samples; must be comfortable with handling blood or tissue samples.
- Basic understanding of HBRA and PDPA.
- Great leadership and willing to take up ownership of assigned tasks.
- Good memory, strong organization and meticulous in database and biobank management.
- Analytical, self-confident and mature personality.
- Responsible and passionate about oncology clinical research.
- Able to work both independently and with other team members under pressure and tight deadlines.

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